منابع مشابه
Pathogenesis of post-lyme disease symptoms.
TO THE EDITOR—In an effort to understand the pathogenesis of post-Lyme disease symptoms, the article by Strle et al estimated the levels of 15 cytokines and an additional 11 chemokines in erythema migrans patients from Slovenia [1]. Their finding of elevated levels of the type 17 helper T-cell (T H 17)–associated interleu-kin 23 (IL-23) in some of the patients with persistent symptoms is a valu...
متن کاملTreatment trials for post-Lyme disease symptoms revisited.
The authors of 4 National Institutes of Health-sponsored antibiotic treatment trials of patients with persistent unexplained symptoms despite previous antibiotic treatment of Lyme disease determined that retreatment provides little if any benefit and carries significant risk. Two groups recently provided an independent reassessment of these trials and concluded that prolonged courses of antibio...
متن کاملPost-Lyme disease syndrome
About 10% of patients with Lyme disease continue to experience musculoskeletal pain and cognitive dysfunction after recommended antibiotic treatment. This condition is called post-Lyme disease syndrome (PLDS) or post-treatment Lyme disease syndrome. These two terms are used interchangeably. The pathogenesis of PLDS has been controversial. The hypothesis that patients with PLDS may harbor hidden...
متن کاملInsight into the Pathogenesis of Lyme Disease
Lyme disease is the most common vector-borne disease in the United States and Europe, caused by a tick-borne spirochete, Borrelia burgdorferi. Life cycle alternation between arthropod and mammals enhanced B. burgdorferi to adapt to two diverse niches. Although B. burgdorferi infection in these reservoir hosts appears asymptomatic, infection in human can typically cause inflammation in the skin,...
متن کاملPost-Lyme borreliosis syndrome: a meta-analysis of reported symptoms.
BACKGROUND This meta-analysis compares the prevalence of fatigue, musculoskeletal pain, and neurocognitive difficulties in patients who have had Lyme borreliosis (LB) and control subjects without LB. METHODS Titles and abstracts in PubMed were reviewed for studies with data on the symptoms listed above that compared patients who had had LB with controls from the general population. Five studi...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2014
ISSN: 1058-4838,1537-6591
DOI: 10.1093/cid/ciu341